Friday, May 12, 2023     8:00 AM – 10:00 AM ET     Room 201

Block Symposium

Tumor Cellular Therapy

Chairs

• Gregoire Altan-Bonnet, NCI, NIH
• Tessa Bergsbaken, Rutgers New Jersey Med. Sch.

Speakers

• Adam Kenet, NCI, NIH, The 1000 mouse experiment: quantifying the variability of tumor response to CAR T cell therapy
• Emily Simon Rav, Univ. of Texas MD Anderson Cancer Ctr., Targeting CD70 using CAR NK cells to enhance NK cells cytolytic effect against osteosarcoma
• Kole R. DeGolier, Univ. of Colorado Anschutz Med. Campus, Antigen experience history directs distinct functional states of CD8⁺ CAR T cells during the anti-leukemia response
• Jennifer Cimons, Univ. of Colorado Anschutz Med. Campus, T-bet overexpression modulates CAR T cell effector functions
• Asmaa Mohamed, Geisel Sch. of Med., Dartmouth Col., CD4 depletion enhances the efficacy of Super2 IL-33 armored CAR T cell against solid tumors and leads memory formation of both endogenous and CAR T cells
• Menglin Cheng, Rutgers Sch. of Grad. Studies, Investigating tissue-resident memory T cell differentiation of CAR T cells reveals an unexpected role for CD69
• Jing Wang, Chinese Univ. of Hong Kong, Investigating the role of HDAC8 in CD4⁺ T cells