Saturday, May 13, 2023 10:15 AM – 12:15 PM ET Room 206
Block Symposium
The Tumor Microenvironment: Novel Immune Checkpoints and Mechanisms of Immune Suppression
Chairs
- Defne Bayik, Univ. of Miami
- Jun Wang, New York Univ.
Speakers
- Juyeun Lee, Cleveland Clin. Fndn., Loss of testosterone leads to impaired T cell function via glucocorticoids in mouse glioblastoma models
- Lucas F. Loffredo, Columbia Univ. Irving Med. Ctr., Exploring the effects of tissue structural cell and tumor cell heparan sulfate on immune system trafficking, activation, and intercommunication via amphiregulin
- Ameet A. Chimote, Univ. of Cincinnati Col. of Med., A novel ion channel-mediated mechanism facilitates the inhibitory effect of exosomes on anti-tumor immune responses
- Ru Wen, Stanford Univ. Sch. of Med., Siglec-7/9 are novel immune checkpoints for prostate cancer
- Gabriel J. Rodriguez-Garcia, Vanderbilt Univ., Tumor cell secretome induces the expression of the immune checkpoint NKG2A on CD8+ T cells
- Qiao Lu, New York Univ. Grossman Sch. of Med., A membrane-associated inhibitory axis of MHC-I presentation for cancer immune evasion
- Venkata Krishna Kanth Makani, Univ. of Pittsburgh, Discovery of human papilloma virus and patient-specific neoantigens targeted by CD8+ T cells in HNSCC
