Sunday, May 14, 2023 8:00 AM – 10:00 AM ET Room 207A
Block Symposium
Pathogenesis to SARS-CoV-2 Infection
Chairs
- Pablo Penaloza-MacMaster, Northwestern Univ. Feinberg Sch. of Med.
- Robin Stephens, Rutgers New Jersey Med. Sch.
Speakers
- Solomon Taye Sima, Rutgers Univ. New Jersey Med. Sch., Immunoregulatory roles of TGF-β and IL-4 during mouse-adapted SARS-CoV-2 infection
- Shailendra Kumar Verma, La Jolla Inst. for Immunology, SARS-CoV-2 Delta requires human ACE2 but not human TMPRSS2 to infect mice and elicits greater lung injury and adaptive immune response than Omicron in human ACE2 knock-in mice
- Vadim I. Pivniouk, Univ. of Arizona, IL-13 protects epithelial cells from SARS-CoV-2 infection by inhibiting early ACE2-mediated events
- Emiko Urano, Natl. Inst. of Biomed. Innovation, Hlth. and Nutrition, Japan, Understanding of SARS-CoV-2 pathogenicity in COVID-19 cynomolgus macaque model and consideration of its reinfection
- Paoline Laurent, Hosp. for Special Surgery, Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19
- Fernanda Ana-Sosa-Batiz, La Jolla Inst. for Immunology, A new mouse model expressing human ACE2, TMPRSS2, and FCGRT for evaluating human antibody responses to SARS-CoV-2
- Lisa K. Ryan, Univ. of Louisville, SARS-CoV2 decreases human beta-defensin-1 and FoxI1 in the oral cavity without affecting CFTR